Brain, liver, longevity: 3 ways MB helps

"Everything is simpler than you think and at the same time more complex than you imagine" - Goethe.

What if a single compound could enhance your mitochondrial function, improve brain health, and protect against inflammation? Methylene blue is proving to be more than just a historical curiosity - it’s a modern health game-changer.

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Let's explore methylene blue, an interesting compound that started as a simple dye but became an important medicine. Created in 1876 for coloring fabrics, scientists later discovered it could fight harmful microbes. Today, hospitals worldwide use it to treat various conditions, and it's gaining attention from health enthusiasts for its wide range of benefits.

How methylene blue works in your body.

Inside each cell, there's a process called the electron transport chain that turns the food you eat into energy (ATP). Methylene blue acts like a shortcut in this chain by carrying electrons directly to oxygen. This makes energy production more efficient, especially when cells aren't working their best.

Key health benefits.

Better cell energy production.

Even if you're healthy, small doses of methylene blue can improve how your cells make energy. It helps cells use oxygen more effectively and produce more ATP. Your body can perform better, from healing wounds to producing important brain chemicals.

Brain health support.

The most exciting discovery involves Alzheimer's disease. A special form called LMTM (hydromethylthionine) has shown remarkable results. It slows both mental decline and brain shrinkage in patients with mild to moderate Alzheimer's. What's really impressive is that it works three times better than current treatments, even at low doses.

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Protecting your liver.

Methylene blue helps protect against fatty liver disease by:

• Activating SIRT1, often called the "longevity gene," which helps maintain energy balance

• Increasing fat burning and decreasing fat production in the liver

• Reducing inflammation

• Helping your liver process hormones like estrogen more effectively

It acts as a substitute electron acceptor, essentially mimicking the role of oxygen in the estrogen breakdown process. This means that even in less-than-ideal conditions, methylene blue helps your liver continue its crucial task of managing estrogen levels. 

When combined with B vitamins, especially B1, B2, and B3 (niacinamide), methylene blue helps your liver break down excess hormones more efficiently.

Fighting Inflammation.

Methylene blue blocks several types of inflammation in your body by stopping specific protein complexes (called inflammasomes) that trigger inflammation. This makes it potentially helpful for various inflammatory conditions. In studies with mice, it even helped them survive severe inflammation, suggesting it could help with serious conditions like sepsis.

Additional benefits.

• Helps protect against EMF exposure from wireless devices

• Promotes healthier, more youthful-looking skin

• Supports bone health, especially as we age

• It can help prevent damage during heart attacks if given quickly enough

Before using methylene blue, understand these important points:

1. Higher doses can temporarily turn your urine and tongue blue (this is harmless but surprising)

2. People taking antidepressants (SSRIs) should be very careful, as combining them can cause dangerous side effects

3. If you have kidney problems or a genetic condition called G6PD deficiency, you should avoid methylene blue

4. Common side effects include mild stomach issues like nausea and diarrhea

5. Some people might experience headaches or confusion

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How to use methylene blue safety.

• Only use pharmaceutical-grade methylene blue prescribed by a doctor

• The recommended daily dose is 3-5 mg (much lower than what's used in emergencies)

• Take one day off per week if you're using it long-term

• Avoid methylene blue solutions as they become less effective after 48-72 hours

Getting and using methylene blue.

There are three types available:

1. Industrial-grade (never use this)

2. Chemical-grade (laboratory-grade - not for human use)

3. Pharmaceutical-grade (the only safe option for people)

You'll need a prescription from a doctor to get pharmaceutical-grade methylene blue. It's best to get your prescription filled at a compounding pharmacy, as regular pharmacies usually only carry expensive IV versions.

Never use methylene blue, which is meant for fish tanks or industrial purposes, as these can contain harmful impurities that could make you sick. Always talk to your healthcare provider before starting methylene blue, as they can determine if it's right for you and prescribe the correct dosage.

From our archive:

Missed this gem? Learn more about fighting inflammation:

🐇 Stop your inflammation

🐇 How diet impacts your inflammation

🐇 Best 2 types workouts improve longevity

Warm regards,
Kos and Helen.