7 secrets your immunity

Do you need to "boost your immunity"?

Let me tell you about two different people and their immune systems.
Man A often catches colds and suffers from spring allergies.
Man B never gets sick and has no known allergies.
Who has a strong immune system and who has a weak one?

Here's a helpful hint: There's no simple right answer.

What truly matters with immunity? It's about responding appropriately.

How can we achieve that? Let's talk about it.

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The concept of immune system strength is actually quite complex. An "active" or "strong" immune system might overreact to harmless things like plant pollen, causing allergies or autoimmune diseases. On the other hand, a "weak" immune system might not respond effectively or produce enough antibodies even after an illness.

There are two types of immunity: inherited and acquired. We are born with inherited immunity, which protects us at a basic level against microorganisms, toxins, and tumor cells. Acquired immunity comes through illnesses and vaccines - there's no other way to get it. This type of immunity can be cellular or humoral (antibody-based).

So what can you do if the traditional idea of immune system "strength" is no longer helpful, but you still want to stay healthy?

A Nature article earlier this year explored the connection between COVID-19 severity and metabolic health. Here are ways to improve immune health:

1. Find the true reasons for frequent colds or excessive weakness (like feeling exhausted by 2 PM even when not sick).

2. Identify underlying inflammation that stresses your immune system.

3. Check your metabolic health.

4. Rule out insulin resistance.

5. Examine digestive health - look for low-grade conditions like gastritis that might prevent proper protein absorption.

6. Check for nutrient deficiencies, starting with iron, then zinc and copper.

Why is metabolic health important? 

Large studies published in Nature found that obesity is a strong, independent factor increasing the risk of illness and mortality. New data suggests that visceral obesity and blood sugar levels (both in diabetic and non-diabetic ranges) play significant roles. Researchers discovered that obesity and diabetes can weaken immune memory, reducing antibody levels after vaccinations.

Our systematic approach to health includes:

1. Diet

2. Physical activity

3. Stress management techniques

4. Sleep

5. Identifying nutrient deficiencies

6. Immune system check-up

7. Hormesis training

8. Addressing metabolic issues: insulin resistance and inflammation

Your microbiome is the heartbeat of your immune system.

The microbiome - the vast ecosystem of microbes residing primarily in your colon - was a primary focus of our discussion. These trillions of microorganisms are not merely passive inhabitants but active participants in training your immune system and maintaining overall health. 

These microbes foster a balanced immune response, preventing chronic inflammation, autoimmune disorders and metabolic diseases such as diabetes and obesity. 

In addition, immunity is affected by a leaky gut, a condition in which the epithelial lining of the digestive tract becomes permeable.

This increased permeability allows unwanted substances like endotoxins (lipopolysaccharides, or LPS) and food antigens to enter your bloodstream, triggering immune responses that lead to autoimmune diseases. In fact, in most cases, you cannot have an autoimmune disease unless you have some type of gut dysfunction.

Maintaining the integrity of your gut barrier is paramount. Still, factors such as stress, poor nutrition, environmental toxins and certain medications often compromise this barrier, leading to systemic inflammation and immune dysregulation.

Below is the data from the Nature article. Note that diabetes has higher risks than asthma.

Our complete starter guide to healthy living is designed to address metabolic problems first and foremost.

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Warm regards,
Kos and Helen.