The silent clock

Your cells are running on a molecule you've never heard of—and every year, you're making less of it.

It's called NAD+ (nicotinamide adenine dinucleotide), and it's one of the most important molecules in your body. Think of it as your cellular battery charger. Without it, your mitochondria can't produce energy. Your DNA can't repair itself, and your metabolism slows to a crawl.

Here's the problem: by middle age, your NAD+ levels have dropped by 50% or more. And that decline might be driving many of the symptoms we associate with aging.

The good news? You can do something about it.

Recover Faster. Train Harder. Stay Stronger.

Give Your Muscles the Recovery They Deserve

Tough workouts push your body to the limit—but what if you could bounce back faster, with less soreness?

Replenish. Repair. Recover.

Your body relies on NAD+ to repair cells, reduce inflammation, and optimize muscle recovery. But as you age, NAD+ levels decline, making recovery slower and soreness last longer.

That’s where NAD+ Precursor Boost™ with TMG (Tri-Methylglycine) comes in.

The Science Behind Faster Recovery

After intense exercise, your body experiences oxidative stress, muscle microtears, and inflammation. NAD+ Precursor Boost™ helps:

Support DNA Repair – Reduces muscle fatigue and speeds up healing
Enhance Cellular Energy – Fuels your cells for quicker recovery
Reduce Post-Workout Soreness – Fights inflammation for pain-free movement
Boost NAD+ Production – Helps your body rebuild and recharge

Less Soreness. More Strength. Faster Gains.

Whether you're lifting heavy, running long distances, or just staying active, NAD+ Precursor Boost™ ensures you recover stronger and faster—so you can hit your next workout at full power.

Take Control of Your Recovery Today

Don't let soreness slow you down. Fuel your body's natural repair process with NAD+ Precursor Boost™.

Why NAD+ Matters (And Why You're Losing It)

NAD+ isn't about energy. It's a coenzyme that powers several crucial processes:

What NAD+ does in your body:

• Converts food into cellular energy (ATP)

• Activates sirtuins—proteins that regulate aging, metabolism, and DNA repair

• Helps repair damaged DNA through PARP enzymes

• Regulates inflammation and immune function

• Controls your circadian rhythm

Why your levels drop with age:

Your body faces a triple threat as you get older:

1. You make less - NAMPT, the key enzyme that recycles NAD+, declines with age

2. You use more - Chronic inflammation triggers CD38, an enzyme that consumes NAD+

3. You waste it - Another enzyme (NNMT) diverts NAD+ building blocks away from production

The result? Less energy, more inflammation, slower repair—the hallmarks of aging.

What the Science Shows

In animals, boosting NAD+ has produced remarkable results:

• Extended healthspan (years of healthy life)

• Improved muscle function and exercise capacity

• Enhanced metabolism and insulin sensitivity

• Reduced inflammation

• Better cognitive function

In humans, the story is still unfolding—but it's promising.

A 2024 study published in Nature used a multi-ingredient supplement approach and found:

• 26.5% average increase in blood NAD+ after 4 weeks

• Some participants saw increases of 65-105%

• Reduced inflammatory markers (especially IL-2)

• Biological age decreased by 1.26 years based on cellular markers

• Lower blood sugar-related damage

Other human trials with NAD+ precursors have shown:

• Improved insulin sensitivity in prediabetic women

• Enhanced physical performance in older adults

• Safe increases in blood NAD+ across various doses

The caveat: A 2023 review found that NAD+ boosters increase NAD+ levels. But, translating that into measurable health improvements has been inconsistent. Some people respond, others see minimal changes.

How to Boost Your NAD+ Levels

Since taking NAD+ doesn't work (it breaks down in your gut), you need to use precursors. Your body converts these into NAD+.

The Main Players

1. NMN (Nicotinamide Mononucleotide)

• One step away from becoming NAD+

• Most-studied in recent trials

• Dosage: 250-500mg daily (studies tested up to 2000mg)

• Best for: Direct conversion to NAD+

2. NR (Nicotinamide Riboside)

• FDA-approved at 300mg/day

• Longer track record of safety studies

• Dosage: 300mg (approved) to 1000mg+ (research doses)

• Best for: Established safety profile

3. Niacin/Nicotinamide (Vitamin B3)

• Found in many foods

• Most bioavailable precursor

• Note: High-dose niacin can cause flushing

The Smarter Approach: Multi-Target Strategy

Recent research suggests the most effective approach addresses many problems at once:

What to consider combining:

• NAD+ precursor (NMN or NR)

• NAMPT activators (alpha-lipoic acid, quercetin)

• CD38 inhibitors (apigenin from parsley extract)

• NNMT inhibitors (EGCG from green tea)

This is the approach that produced the best results in the 2024 human trial.

Natural Food Sources

While you can't boost NAD+ through diet alone, these foods contain precursors:

• Fish (tuna, salmon)

• Chicken and turkey

• Mushrooms

• Green vegetables

• Milk and dairy

The Practical Guide

If you're considering NAD+ supplementation:

Start with: 250-500mg NMN or 300mg NR daily

Take: In the morning (may affect sleep if taken late)

Expect: Results vary between individuals

Timeline: Studies show effects within 2-8 weeks

Safety: Well-tolerated with minimal side effects

Reality check:

• You might be a high responder (65%+ increase) or minimal responder

• Blood NAD+ increases don't always mean tissue increases

• Long-term human data is still limited

• This isn't a magic bullet—lifestyle factors still matter most

Who Should Consider NAD+ Boosters?

Best candidates:

• People over 40 experiencing energy decline

• Those focused on metabolic health and healthy aging

• Athletes looking to optimize recovery

• Anyone with family history of age-related metabolic issues

Talk to your doctor first if:

• You're on blood thinners or blood pressure medication

• You have kidney or liver disease

• You're pregnant or breastfeeding

The Bottom Line

NAD+ sits at the intersection of energy metabolism, DNA repair, and healthy aging. The science is compelling enough that it's worth attention, especially as you age.

The research shows:

• NAD+ decline is real and measurable

• Precursors increase NAD+ levels in humans

• Some people see significant benefits

• We need more long-term studies

Is it the fountain of youth? No. Focus first on nutrition, regular movement, good sleep, and stress management. Then NAD+ may be a good addition.

Key Studies Referenced

1. Systems approach to NAD+ supplementation - Nature (2024)

2. NAD+ metabolism and aging - Nature Reviews (2021)

3. Safety of NMN supplementation - Frontiers in Nutrition (2022)

4. NAD+ precursors comprehensive review - PMC

5. Critical review of NR supplementation - Science Advances (2023)